South Carolina Board of Pharmacy

2025-2026 Annual Pharmacist Renewal Appplication

If your Pharmacist license has lapsed/expired, complete the Pharmacist License Reinstatement.

If your Pharmacy Technician Registration and/or State Certified Pharmacy Technician Registration has lapsed/expired within the last year, you must complete the Lapsed Pharmacy Technician Registration. Click here to obtain the application.

If your Pharmacy Technician Registration and/or State Certified Pharmacy Technician Registration is lapsed/expired 2 years or more, you must complete the Pharmacy Technician Registration Reinstatement application. Click here to obtain the application.

Login Portal to Renew Electronically

In-State Renewal Applications

In State (Resident) Renewal Applications

All resident permit holders may upload permit renewal applications and pay renewal fees electronically via the Board’s e-Services Document Submission system.

Renewal Deadlines

Timely Renewal Deadline — May 31, 2025

To avoid the $50 late fee, facility renewal applications must be submitted on or before May 31, 2025. Applications submitted by mail must be postmarked on or before May 31, 2025.




Permit Expiration Date — June 30, 2025

A permit which has not been renewed before July 1, 2025, enters Lapsed status. To prevent a lapsed permit, facility renewal applications must be submitted on or before June 30, 2025. Mailed applications must be postmarked on or before June 30, 2025. Beginning July 1, 2025, lapsed permits will incur an additional $10 per day penalty, up to $25,000

Electronic Application Submission and Payment

To submit an electronic renewal application, along with required supporting documents, using the Board’s Document Submission system. The system will then allow for payment of the annual renewal fee online using a debit/credit card or check.

Document Submission Instructions

*THIS IS NOT AN ONLINE RENEWAL. THIS ALLOWS FOR UPLOADING AND PAYMENT.

Document Submission allows permit holders to upload application documents and pay fees electronically, rather than submit applications and documents to the Board via mail

• EMS for Profit Only
• Medical Gas/Legend Device Permit
• Federally Qualified Health Center (FQHC) Permit
• 503B Outsourcing Permit
• Health System Non-Dispensing Drug Outlet Permit
• Central Fill Pharmacy Permit
• Narcotic Treatment Program Permit
• Narcotic Treatment Program Satellite Permit
• Non-Dispensing Drug Outlet Permit (not for EMS Non-Dispensing)

Click here to sign into Document Submission with the User ID located on the renewal notice. The renewal application is available through this link.

To recover/retrieve your User ID, click on “Forgot username.” To reset your password, click on “Forgot password.”

If you are an EMS non-profit, you will not be able to use Document Submission. Print and complete the application. Then email the renewal application to contact.pharmacy@llr.sc.gov.

2025-2026 EMS Non-Profit Non-Dispensing Permit Renewal

Only the below permits are available for online renewal:

• Pharmacy Permit
• Manufacturer/Repackager Permit
• Wholesale Distributor Permit
• Third Party Logistics Permit

Click on "Log In Portal" to begin the online renewal.

Non-Resident Renewal Applications

All non-resident permit holders may upload permit renewal applications and pay renewal fees electronically via the Board’s e-Services Document Submission system.

Renewal Deadlines

Timely Renewal Deadline – May 31, 2025

To avoid the $50 late fee, facility renewal applications must be submitted on or before May 31, 2025. Applications submitted by mail must be postmarked on or before May 31, 2025.

Permit Expiration Date – June 30, 2025

A permit which has not been renewed before July 1, 2025, enters Lapsed status. To prevent a lapsed permit, facility renewal applications must be submitted on or before June 30, 2025. Mailed applications must be postmarked on or before June 30, 2025. Beginning July 1, 2025, lapsed permits will incur an additional $10 per day penalty, up to $25,000.

Electronic Application Submission and Payment

To submit an electronic renewal application, upload a completed renewal application, along with required supporting documents, using the Board’s Document Submission system. The system will then allow for payment of the annual renewal fee online using a debit/credit card or check.

*THIS IS NOT AN ONLINE RENEWAL* Document Submission allows permit holders to upload application documents and pay fees electronically, rather than submit applications and documents to the Board via mail.

The below Non-Resident renewal applications are available for Document Submission:

• Non-Resident Medical Gas/Legend Device Permit
• Non-Resident 503B Outsourcing Permit
• Non-Resident Central Fill Pharmacy Permit
• Non-Resident Third Party Logistics Provider Permit
• Non-Resident Non-Dispensing Pharmacy Permit
• Non-Resident Wholesale/Distributor Permit
• Non-Resident Manufacturer/Repackager Permit
• Non-Resident Virtual Wholesale/Distributor Permit
• Non-Resident Virtual Manufacturer/Repackager Permit

Click here to sign into Document Submission with the UserID located on the renewal notice. The renewal application is available through this link.



To recover/retrieve the User ID, click on “Forgot username.” To reset the password, click on “Forgot password.”

Paper Application Submission and Payment

To submit a paper renewal application, mail the completed renewal application, along with required supporting documents, to:

South Carolina Board of Pharmacy
110 Centerview Dr.
Columbia, SC 29210

Online Renewal

Only the below permit is available for online renewal:

• Non-Resident Pharmacy Permit

Click on "Log In Portal"to begin online renewal.